Continuation of CE 328.

A continuation of CE 427.

Properties of solids, which chemical engineers need to understand and exploit in regard to chemical processing and industrial equipment; how chemical and physical structures determine the uses of the products of the chemical industry. Crystal structure, crystal defects, and how they dominate mechanical properties. Thermal and electrical properties of solids. Polymer structures and properties. Corrosion: mechanisms and prevention.

Properties of solids, which chemical engineers need to understand and exploit in regard to chemical processing and industrial equipment; how chemical and physical structures determine the uses of the products of the chemical industry. Crystal structure, crystal defects, and how they dominate mechanical properties. Thermal and electrical properties of solids. Polymer structures and properties. Corrosion: mechanisms and prevention.

Equips engineering students with the fundamental concepts of process control design. An introduction to the benefits of having a good control process is followed by the definitions of the control objectives, feedback and feedforward control, and the various types of variables found in process control problems. Includes the development of dynamic mathematical models for simple processes, using mass and energy balances. Introduces mathematical tools (Laplace Transformations) that help solve such mathematical models as well as define the transfer functions of typical process systems (first and second order systems). Introduces the controller concept, together with the basic principles behind the feedback control loop and its stability characteristics.

Classifies polymers with respect to structure and formation reaction; relations between chemical structure and physical properties; some characteristics of polymer solutions; mechanical behavior; and engineering properties.

Economic aspects of chemical engineering: time value of money, including interest and investments; alternative methods of analysis, such as annual costs, percent, and rate of return; process costs and concepts, including cost estimation, and chemical equipment and plant costs; a small cost-related process design project.

Introduces fundamentals of process design utilizing computer techniques and methods.

Introduces principles of process control. Feedback, feedforward, and open-loop control. Effects of major controller actions on typical processes: on-off, proportional, integral, and derivative. Predicts the dynamic response of a process through mathematical models. Frequency response analysis; introduces tuning of a system.

Introduces principles of process control. Feedback, feedforward, and open-loop control. Effects of major controller actions on typical processes: on-off, proportional, integral, and derivative. Predicts the dynamic response of a process through mathematical models. Frequency response analysis; introduces tuning of a system.

Significant microbial products, organisms, and substrates; directing microbial activity by random mutation and recombinant DNA; kinetics of growth and product formation; types of fermenters; aeration and agitation; scale-up; sterilization; product separation.

Discusses the application of biological transport and kinetics principles in normal human physiology, disease states and during treatment. Focuses on selected aspects of the nature of receptor-ligand interactions, cell adhesion mechanics, drug delivery, and biological transport in organs. Topics include experimental methods for measuring receptor-ligand interactions, models for receptor-ligand binding and analysis of real data, methods for measuring and analyzing cell adhesion both in suspension and substrate based assays, cardiovascular fluid mechanics, blood components and blood viscosity measurements, flow in arteries and microcirculation, fahraeus effect, engineering principles for drug delivery including diffusion and convective transport of drugs to organs, pharmacokinetic modeling, drug delivery system design and controlled drug release, transport between blood and tissues, and between kidneys and tumors.

Introduces biomedical engineering with emphasis on vascular engineering. Gives students an understanding of how quantitative approaches can be combined with biological information to advance knowledge in the areas of thrombosis, inflammation biology and cancer metastasis. Emphasizes cellular and molecular bioengineering methods.

Topics include mathematical techniques for optimization, genomics-genome sequencing, genome sequence annotation, metabolic networks, linear and quadratic optimization for metabolic network optimizations, experimental approaches to metabolic network optimization, c-labeling for metabolic flux determination, examples of using such approaches for high value chemical production optimization, background on cell signaling, biochemical/biophysical description of major signaling pathways including techniques for collecting experimental data, strategies for modeling signaling networks, examples of utilizing a mathematical framework to predict (and manipulate) cellular behavior in response to specific stimuli, examples of cell signaling in disease states, background and description of genetic networks, experimental approaches to genetic networks, strategies for modeling genetic networks, examples of describing/predicting genetic network behavior using mathematical tools, and an overview of genomic and proteomic methodologies.

Introduction to protein engineering and design. This course teaches students to think of protein as an entity that can be engineered using molecular tools in order to achieve novel physical and chemical properties. Students first learn the fundamentals of protein structure and how protein structure dictates function, which includes discussion of protein structure, biochemistry, molecular biology techniques, the basics of physical and organic chemistry, and molecular modeling through computer visualization. Additionally, students learn different protein design strategies, including knowledge-based design, computational protein design, and directed evolution, that are commonly used for protein engineering. Examples of engineered proteins with novel structural and functional properties are extensively discussed to illustrate how design principles are applied to real life problems.

Introduces aerosol science and technology at a senior undergraduate/beginning graduate level. Provides the knowledge and skills needed to understand and predict the production, transport, and other behavior of aerosols and introduces technologies for producing, measuring, and collecting them.

Dispersed systems (e.g., suspensions, emulsions, foams, and other systems) in which surface effects dominate behavior. Surface tension. Gas adsorption and adsorption from solution. Effects of surface charge. Wetting, detergency, adhesion. Transport processes dominated by surface tension.

Topics in the field of specialization selected with the permission of the instructor.

Topics in the field of specialization selected with the permission of the instructor.

Exposes students to a broad range of industrial problems and the techniques to solve them using a project-oriented approach.

Hands-on experience in the field. Problems vary from year to year, and may include chemical process studies, engineering materials studies, or computer-based analysis of specific chemical engineering problems. Internship assignments follow student preferences where possible and require consent of a faculty members who guide the work. Typically, students are required to spend approximately ten unpaid hours per week at an industrial site. Grading is based in part on written and oral reports that are required upon completion of the internship.

Accepted seniors pursue a specialized, independent study leading to an Honors thesis or project.

Students collaborate with faculty research mentors on an ongoing faculty research project or conduct independent research under the guidance of a faculty member. This experience provides students with an inquiry-based learning opportunity and engages them as active learners in a research setting.

Students should be accepted for work on a specific topic by a member of the teaching staff of the chemical engineering department.